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Mi Hee Lim

Mi Hee Lim

KAIST · Chemistry

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Professor

About

생체무기화학, 화학신경과학, 화학생물학을 연구한다. 금속이 관여하는 생물학적 네트워크와 알츠하이머·파킨슨병 등 퇴행성 뇌질환의 연관성을 규명한다. 구리 등 금속과 아밀로이드-베타 펩타이드의 상호작용을 분석하고, 합성화학·분광법·생화학 기법을 활용해 진단 및 치료 도구로 기능하는 화학 시약을 개발한다.

Research keywords

Bioinorganic ChemistryMetal Enzymes

Selected publications

  • Strategic Physicochemical Tuning: Amphiphilic Polymers as Molecular Regulators of Amyloid Aggregation and ToxicityChemical Science · 2026
  • A Prodrug Approach for Activity-Based Chemical Modulation toward Multiple Pathological Targets in Alzheimer's DiseaseSmall · 2026
  • Positional Isomerism Tunes Molecular Reactivities and Mechanisms toward Pathological Targets in DementiaJournal of the American Chemical Society · 2026
  • Interactions with Tau's Microtubule-Binding Repeats Modulate Amyloid-β Aggregation and ToxicityNature Chemical Biology · 2025
  • Conformational and Functional Changes of the Native Neuropeptide Somatostatin Occur in the Presence of Copper and Amyloid-βNature Chemistry · 2022

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