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Microbial Engineering Lab

Microbial Engineering Lab

KAIST · Graduate School of Engineering Biology

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Professor

Prof. 이남일

Professor's page · publications

About

KAIST 공학생물학대학원 이남일(Namil Lee) 교수 연구실이다. 방선균(actinomycetes) 등 미생물의 합성생물학·시스템 대사공학을 통해 항생제·항암제 등 천연물 생산과 미생물 세포공장 기반 바이오생산을 연구한다.

Research keywords

Microbial EngineeringBioproduction

Selected publications

  • Retrobiosynthesis of unnatural lactams via reprogrammed polyketide synthaseNature Catalysis · 2025
  • Regulatory orchestration of FK506 biosynthesis in Streptomyces tsukubaensis NRRL 18488 revealed through multi-omic data analysisiScience · 2025
  • Decoding multidimensional regulatory networks in Streptomyces to accelerate natural product discovery and productionNatural Product Reports · 2026
  • Re-classification of Streptomyces venezuelae strains and mining secondary metabolites biosynthetic gene clustersiScience · 2021
  • Systems and synthetic biology approaches on Streptomyces for enhancing the production of secondary metabolitesNatural Product Reports · 2021
  • Iron competition triggers antibiotic biosynthesis in Streptomyces coelicolor during coculture with Myxococcus xanthusISME Journal · 2020

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