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Donghak Kim

Donghak Kim

Konkuk University · Biological Sciences

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Professor

Prof. 김동학

Professor's page · publications

About

김동학 교수 연구실(분자약리독성학 연구실)은 건국대 생명과학과 소속으로, 시토크롬 P450 효소에 의한 약물 및 외래화합물(xenobiotics) 대사와 인체 독성을 연구한다. 효소학·HPLC·질량분석·정지유동(stopped-flow) 분광법 등을 활용해 단백질 구조와 기능 기전, 효소 저해제 설계, 화합물 라이브러리 HTS 기반 신약개발을 수행한다.

Research keywords

분자약리독성학

Selected publications

  • Molecular and functional characterization of Drosophila melanogaster CYP6A2 in response to pesticides and terpenoidsInsect Biochemistry and Molecular Biology · 2026
  • Molecular insights into CYP19A1 mutations and their role in estrogen productionArchives of Biochemistry and Biophysics · 2025
  • Steroidogenic cytochrome P450 enzymes as drug targetToxicological Research · 2024
  • Structural Insights into the Interaction of Terpenoids with Streptomyces avermitilis CYP107P2Biomolecules & Therapeutics · 2024
  • Catalytic enhancements in cytochrome P450 2C19 by cytochrome b5Toxicological Research · 2024
  • Functional characterization of allelic variations of human cytochrome P450 2C8International Journal of Molecular Sciences · 2023

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