Synthetic Biology Lab
Synthetic Biology Lab
KAIST · Bio and Brain Engineering
Professor
Prof. 이혜선
Professor's page · publicationsAbout
이혜선 교수 연구실(ICE Lab, Immunological and Cellular Engineering Laboratory)은 KAIST 바이오및뇌공학과 소속으로, 합성생물학을 기반으로 면역세포 치료·진단, 면역세포 엔지니어링, 백신/약물전달 시스템을 연구한다. 임상에서 영감을 받은 합성 유전자 스위치와 약물로 제어되는 CAR 회로 등 인간 세포 기능을 정밀 제어하는 기술을 개발한다. 이혜선 교수는 서울대 동물생명공학 박사 후 보스턴대 생의공학 박사후연구원을 거쳐 2023년 6월 부임했다.
Research keywords
Selected publications
- Multidimensional control of therapeutic human cell function with synthetic gene circuitsScience · 2022
- High-performance multiplex drug-gated CAR circuitsCancer Cell · 2022
- Nasal immunization with mannan-decorated mucoadhesive HPMCP microspheres containing ApxIIA toxin induces protective immunity against challenge infection with Actinobacillus pleuropneumoiae in miceJournal of Controlled Release · 2016
- Mannan decorated thiolated Eudragit microspheres for targeting antigen presenting cells via nasal vaccinationEuropean Journal of Pharmaceutical Sciences · 2015
- Recombinant interleukin 6 with M cell-targeting moiety produced in Lactococcus lactis IL1403 as a potent mucosal adjuvant for peroral immunizationVaccine · 2015
Other labs in this department
- AI-Brain Mechanism LabRecruiting
Yul HR Kang
AI and brain mechanism comparison, decision-making under uncertainty, vision-based autonomous driving, computational cognitive neuroscience
- Brain Technology LabRecruiting
Young-Gyun Park
Brain research technology development, brain mapping, novel brain networks, convergent imaging, ultrasound vocalization, memory, Parkinson's disease
- Ultrasound Engineering LabRecruiting
Eunyeong Park
Ultrasound engineering, ultrasound imaging/therapeutic systems, photoacoustic imaging
- Therapeutic Bioengineering LabRecruiting
Ji Ho Park
Biomaterials, drug delivery, nanomedicine, therapeutic bioengineering
- Nanomedicine LabRecruiting
Min-Jun Baek
Nano drug delivery systems, pharmaceutics, phototheranostics
- Molecular Diagnostics LabRecruiting
Sungmin Son
Molecular diagnostics, Cas13 gene scissors, super-resolution imaging, intercellular communication, bio-MEMS