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Dae-Sik Lim

Dae-Sik Lim

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Professor

About

분자종양유전학 연구실(Laboratory of Molecular Oncogenetics)을 이끈다. Hippo 신호전달 경로와 핵심 인자 YAP/TAZ를 중심으로 세포 분열·분화, 성체줄기세포, 간질환 및 암 발생 기전을 연구하며 KAIST 줄기세포센터장을 맡고 있다.

Research keywords

Cancer BiologyCell SignalingTumor Microenvironment

Selected publications

  • Epithelial WNT secretion drives niche escape of developing gastric cancerMolecular Cancer · 2025
  • Two Hippo signaling modules orchestrate liver size and tumorigenesisEMBO Journal · 2023
  • Hippo-YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin expression from fat massNature Metabolism · 2024
  • PRMT1 promotes pancreatic cancer development and resistance to chemotherapyCell Reports Medicine · 2024
  • Formation of a giant unilocular vacuole via macropinocytosis-like process confers anoikis resistanceeLife · 2024

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